abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Genkwa flos, as a traditional herb, is the dried flower buds of Daphne genkwa Sieb.et Zucc. It is used in traditional medicine for the treatment of cough, sore throats, edema. AIM OF THE STUDY:The study aimed to explore a new mathematical method for multivariate evaluation, investigate t...

authors： Zhou DC,Zheng G,Jia LY,He X,Zhang CF,Wang CZ,Yuan CS

更新日期：2021-03-25 00:00:00

abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tao Hong Si Wu Decoction (THSWD) is a traditional prescription for blood management in traditional Chinese medicine, THSWD consists of Paeoniae Radix Alba (Paeonia lactiflora Pall.), Rehmanniae Radix Praeparata (Rehmannia glutinosa (Gaertn.) DC.), Angelicae Sinensis Radix (Angelica sinens...

authors： Xia W,Hu S,Wang M,Xu F,Han L,Peng D

更新日期：2021-03-25 00:00:00

abstract：ETHNOPHARMACOLOGICAL RELEVANCE:QingYan Formula has been traditionally used to tonify kidney and benefit essence, and QingYan Formula 70% ethanol extracts (QYFE) showed estrogen-like effect on reproductive system in our previous studies. However, there were no reports of QYFE on bone. AIM OF THE STUDY:This study offere...

authors： Zhao Y,Xu Y,Zheng H,Lin N

更新日期：2021-03-25 00:00:00

abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Artemisia biennis Willd. (Dermane in Persian) has been used as an antinociceptive remedy in Iranian folkloric medicine. OBJECTIVE:The aim of the present study was to evaluate the anti-nociceptive effects of Artemisia biennis Willd. aerial part essential oil (ABAEO) on male Swiss mice. M...

authors： Zarei M,Ahmadimoghaddam D,Mohammadi S

更新日期：2021-03-25 00:00:00

abstract：ETHNOPHARMACOLOGICAL RELEVANCE:FuFang ZhenZhu TiaoZhi (FTZ) is a hospitalized traditional Chinese medicine herbal formula with documented metabolic benefits. Polycystic ovary syndrome (PCOS) characterized by ovarian dysfunction and insulin resistance represents one of the most common endocrine disorders in close associ...

authors： Xu Y,Tang J,Guo Q,Xu Y,Yan K,Wu L,Xie K,Zhu A,Rong X,Ye D,Guo J

更新日期：2021-03-25 00:00:00

abstract：ETHNOPHARMACOLOGICAL RELEVANCE:In Africa, traditional medicine encompasses a diverse range of practices, including herbalism and spiritualism, where some diseases are believed to be "African" since they can only be traditionally treated. Indigenous knowledge on the management of "African" diseases using medicinal plant...

authors： Gumisiriza H,Sesaazi CD,Olet EA,Kembabazi O,Birungi G

更新日期：2021-03-25 00:00:00

abstract：ETHNOPHARMACOLOGICAL RELEVANCE:G. pentaphyllum, also known as Jiao-Gu-Lan, has been used traditionally as folk remedies for many diseases, including diabetes mellitus, metabolic syndrome, aging, and neurodegenerative diseases in China and some countries in East and Southeast Asia. It is considered as an "immortality he...

authors： Nguyen NH,Ha TKQ,Yang JL,Pham HTT,Oh WK

更新日期：2021-03-25 00:00:00

abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The ethnopharmacological significance of the fruits of Syzygium paniculatum Gaertn (Magenta Cherry) is widely recognized in the Indian traditional medicine system to treat various disorders, such as diabetes, hyperlipidaemia, hypertension, and cardiovascular problems. AIM OF THE STUDY:Th...

authors： Konda PY,Chennupati V,Dasari S,Sharma N,Muthulingam M,Ramakrishnan R,Sade A,Jagadheeshkumar V,Natesan V,Jaiswal KK

更新日期：2021-03-25 00:00:00

abstract：:In this study, we performed an integrated physiological and chloroplast proteome analysis of wheat seedling leaves under salt and osmotic stresses by label-free based quantitative proteomic approach. Both salt and osmotic stresses significantly increased the levels of abscisic acid and methyl jasmonate and led to dama...

authors： Zhu D,Luo F,Zou R,Liu J,Yan Y

更新日期：2021-03-15 00:00:00

abstract：BACKGROUND:Time-restricted feeding (TRF), a key component of intermittent fasting regimens, has gained considerable attention in recent years due to reversing obesity and insulin resistance. To the best of our knowledge, here, we reported for the first time the underlying mechanistic therapeutic efficacy of TRF against...

authors： She Y,Sun J,Hou P,Fang P,Zhang Z

更新日期：2021-03-15 00:00:00

abstract：:Mitochondrial enzymes are targets of newly synthesized drugs being tested for the treatment of neurodegenerative disorders, such as Alzheimer's disease (AD). The enzyme 17β-hydroxysteroid dehydrogenase type 10 (HSD10) is a multifunctional mitochondrial protein that is thought to play a role in the pathophysiology of A...

authors： Fišar Z,Musílek K,Benek O,Hroch L,Vinklářová L,Schmidt M,Hroudová J,Raboch J

更新日期：2021-03-15 00:00:00

abstract：:Soy protein isolates were fermented by three commercial Lactobacillus helveticus strains for a maximum of seven days to investigate the resulting proteolysis. The proteolytic activity of the most active strain (LH88) was further analyzed (LC-MS/MS and GC-MS) and it was shown that the β-conglycinin α subunit 1, β-congl...

authors： Shirotani N,Bygvraa Hougaard A,Lametsch R,Agerlin Petersen M,Rattray FP,Ipsen R

更新日期：2021-03-15 00:00:00

abstract：:This study aimed to comparatively investigate the temperature effect on the kinetic parameters and rate constants representing lipid hydroperoxides (LOOH) formation and decomposition during initiation and propagation peroxidations. The initiation phase was characterized by induction period IP, overall initiation rate ...

authors： Farhoosh R

更新日期：2021-03-15 00:00:00

abstract：:Lactose is an important additive because of its food, pharmaceutical, and cosmetic applications. Among lactose polymorphs, anhydrous β-lactose stands out due to its thermodynamic stability. Thus, a simple method to produce the inter-conversion from monohydrate α-lactose to anhydrous β-lactose was investigated employin...

authors： Lara-Mota EE,Nicolás-Vázquez MI,López-Martínez LA,Espinosa-Solis V,Cruz-Alcantar P,Toxqui-Teran A,Saavedra-Leos MZ

更新日期：2021-03-15 00:00:00

abstract：:The internal blue discoloration of radish root after harvest is a physiological phenomenon that decreases the radish quality. Internal blue discoloration in the roots of 16 varieties of Chinese radish along with the stability of blue pigment under different light, pH, and temperature conditions were investigated. Amon...

authors： Zhang Y,Zhao X,Ma Y,Jiang Y,Wang D,Liang H

更新日期：2021-03-15 00:00:00

abstract：:Cholangiocarcinoma is the second most common primary hepatic cancer, with a rising incidence worldwide. Owing to late diagnosis and limited treatment options, the prognosis for cholangiocarcinoma remains dismal, compelling a search for new treatments. As aspirin exhibits a well-supported chemopreventive effect on comm...

authors： Shen X,Shen X

更新日期：2021-03-15 00:00:00

abstract：:The predictive effect of circulating tumor DNA (ctDNA) in colorectal cancer (CRC) treatment is still highly discussed. The primary objective of our study was to investigate a possible prognostic/predictive value of ctDNA under regorafenib treatment. This prospective multicenter translational biomarker phase II pilot s...

authors： Unseld M,Belic J,Pierer K,Zhou Q,Moser T,Bauer R,Piringer G,Gerger A,Siebenhüner A,Speicher M,Heitzer E,Prager GW

更新日期：2021-03-15 00:00:00

abstract：:This study aimed to prepare anthocyanin-rich microcapsules by spray and freeze-drying complex coacervated double emulsion using gelatin-acacia gum (GE-AG) and chitosan-carboxymethylcellulose (CS-CMC) and to investigate their properties and in vitro release kinetics. Microencapsulation efficiency (MEE) of the microcaps...

authors： Kanha N,Regenstein JM,Surawang S,Pitchakarn P,Laokuldilok T

更新日期：2021-03-15 00:00:00

abstract：:Non-enzymatic electrochemical sensors for the monitoring of reducing sugars in foods has great potential as a rapid in-situ detection method. This development involved the assembly of a nanoporous platinum structure on a screen-printed carbon electrode (SPCE). The modified electrode was then employed as an amperometri...

authors： McCormick W,Muldoon C,McCrudden D

更新日期：2021-03-15 00:00:00

abstract：:This study proposed a novel analytical method for the separation and determination of cobalamin and cobalt in kefir samples by high performance liquid chromatography-inductively coupled plasma-optical emission spectrometry (HPLC-ICP-OES) in addition to determination of cobalamin in HPLC system. Chromatographic paramet...

authors： Bodur S,Erarpat S,Balçık U,Bakırdere S

更新日期：2021-03-15 00:00:00

abstract：:In neurofeedback applications, neural activity is recorded, processed in real-time and fed back to the user in order to facilitate self-regulation of the putative neural mechanisms that underlie cognition and behavior. Numerous studies suggest that neurofeedback interventions are an efficacious treatment particularly ...

authors： Schönenberg M,Weingärtner AL,Weimer K,Scheeff J

更新日期：2021-03-08 00:00:00

abstract：:The noradrenergic locus coeruleus nucleus is an important station in both the ascending and descending pain regulatory pathways. These neurons discharge in tonic and phasic modes in response to sensory stimuli. However, few studies have set out to characterize the electrophysiological response of the locus coeruleus t...

authors： Alba-Delgado C,Mico JA,Berrocoso E

更新日期：2021-03-08 00:00:00

abstract：:The efficacy and tolerability of repetitive transcranial magnetic stimulation (rTMS) in major depression is well-known and documented by existing studies. However, whether rTMS may be effective on suicidal behavior is unclear and needs to be further investigated. This systematic review is aimed to investigate the avai...

authors： Serafini G,Canepa G,Aguglia A,Amerio A,Bianchi D,Magnani L,Dell'Osso B,Pompili M,Fitzgerald PB,Amore M

更新日期：2021-03-08 00:00:00

abstract：:The brain's endocannabinoid system plays a crucial role in reward processes by mediating appetitive learning and encoding the reinforcing properties of substances. Evidence also suggests that endocannabinoids are an important constituent of neuronal substrates involved in emotional responses to stress. Thus, it is cri...

authors： Filbey FM,Beaton D,Prashad S

更新日期：2021-03-02 00:00:00

abstract：:Low grade neuroinflammation has been suggested as one of the underlying mechanisms of many psychiatric diseases as well as cognitive disorders. Interleukin 8 (IL-8), a proinflammatory cytokine produced by many cell types including macrophage and microglia, mainly functions as a neutrophil chemoattractant in the bloods...

authors： Tsai SJ

更新日期：2021-03-02 00:00:00

abstract：:COP9 signalosome subunit 5 (CSN5) plays a key role in carcinogenesis of multiple cancers and contributes to the stabilization of target proteins through deubiquitylation. However, the underlying role of CSN5 in thyroid carcinoma has not been reported. In this research, our data showed that CSN5 was overexpressed in th...

authors： Xie P,Wang H,Fang J,Du D,Tian Z,Zhen J,Liu Y,Ding Y,Fu B,Liu F,Huang D,Yu J

更新日期：2021-03-01 00:00:00

abstract：:Advances in cellular therapies for pediatric patients have created many opportunities for improved survival with reduced morbidity. This article reviews current cellular therapies in pediatric hematological malignancy, including the most updated practices in hematopoietic stem cell transplant and the use of chimeric a...

authors： Kuldanek S,Pasko B,DomBourian M,Annen K

更新日期：2021-03-01 00:00:00

abstract：:In athletes, foot injuries present with a variety of mechanisms, severity, and implications for return to play. Although potentially given less attention than knee and shoulder injuries by the team physician, foot injuries are common and thus require knowledgeable consideration. In this article, we review the anatomy,...

authors： Davis WA 3rd,Yagnik GP

更新日期：2021-03-01 00:00:00

abstract：:A one-stage airlift internal circulation biofilm reactor was continuously operated for 668 days to treat 50 mg/L of ammonia wastewater to pursue the long-term stability of partial nitritation and anammox (PNA) process. The operational performance and microbial community structure of the biofilm and the flocs were inve...

authors： Chen H,Wang H,Yu G,Xiong Y,Wu H,Yang M,Chen R,Yang E,Jiang C,Li YY

更新日期：2021-03-01 00:00:00

abstract：:Radix Astragali (RA) is widely used in traditional Chinese medicine (TCM), and astragaloside IV (AS‑IV) is the most critical component of RA. Previous studies have demonstrated that AS‑IV exerts effects on the myocardium, nervous system and endocrine system, among others. In the present review article, data from studi...

authors： Chen T,Yang P,Jia Y

更新日期：2021-03-01 00:00:00

abstract：:Emerging studies have indicated that the dysregulation of microRNAs (miRNAs or miRs) plays a vital role in the development and metastasis of tumors. However, the role of miR‑93‑5p in esophageal carcinoma (EC) has not been extensively reported. The present study thus focused on the role of miR‑93‑5p and its downstream ...

authors： Cai Y,Ruan W,Ding J,Wei N,Wang J,Zhang H,Ma N,Weng G,Su WK,Lin Y,Zhu K

更新日期：2021-03-01 00:00:00

abstract：:In this study, Lysinibacillus sp. RGS was evaluated to synthesize polyhydroxybutyrate (PHB) from a broad range of pure carbon sources and residual sugars of chemically pretreated sugarcane bagasse (SCB) hydrolysates. Effects of supplementation of nutrients and various experimental variables to enhance PHB accumulation...

authors： Saratale RG,Cho SK,Saratale GD,Ghodake GS,Bharagava RN,Kim DS,Nair S,Shin HS

更新日期：2021-03-01 00:00:00

abstract：:This study aims to develop a novel technology for actual municipal wastewater treatment to achieve rapid sludge sedimentation and high pollutants removal efficiency. The SBRs were modified and operated with periodic addition of 20 μL·L-1 nanofloc®. Results revealed that NH4+-N and chemical oxygen demand (COD) was effi...

authors： He W,Wang Q,Zhu Y,Wang K,Mao J,Xue X,Shi Y

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:Psychological support is available more widely supported by emerging technologies as an addition to face-to-face consultations, more and more people are accessing psychological support using online resources. OBJECTIVE:This research provides insights into the perception of the key factors that affect the ef...

authors： Liu J,Gao L

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The pace of technology development with single-use endoscopy has led to a range of disposable ureteroscopes. We review the development of single-use scopes, deconstruct the basic design and functional characteristics of available devices, and discuss future directions for next-generation platforms. R...

authors： Bahaee J,Plott J,Ghani KR

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Over 70 million people worldwide, including those with neurodegenerative disease (NDD), have been diagnosed with coronavirus disease 2019 (COVID-19) to date. We review outcomes in patients with NDD and COVID-19 and discuss the hypothesis that due to putative commonalities of neuropathogenesis, COVID-1...

authors： McAlpine LS,Fesharaki-Zadeh A,Spudich S

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe and critically discuss the most recent evidence regarding stone management during the coronavirus disease 2019 (COVID-19) and post-COVID-19 era. RECENT FINDINGS:There is a need to plan for resuming the normal elective stone surgery in the post-COVID era, keeping a clear record of all surg...

authors： Proietti S,Basulto-Martinez M,Pavia MP,Luciani L,Gaboardi F,Giusti G

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:Recent advances in artificial intelligence (AI) have shown great promise in detecting some diseases based on medical images. Most studies developed AI diagnostic systems only using eligible images. However, in real-world settings, ineligible images (including poor-quality and poor-location images) that can c...

authors： Li Z,Jiang J,Zhou H,Zheng Q,Liu X,Chen K,Weng H,Chen W

更新日期：2021-03-01 00:00:00

abstract：:The adipokine leptin regulates energy homeostasis through ubiquitously expressed leptin receptors. Leptin has a number of major signaling targets in the brain, including cells of the anterior pituitary (AP). We have previously reported that mice lacking leptin receptors in AP somatotropes display growth hormone (GH) d...

authors： Allensworth-James M,Banik J,Odle A,Hardy L,Lagasse A,Moreira ARS,Bird J,Thomas CL,Avaritt N,Kharas MG,Lengner CJ,Byrum SD,MacNicol MC,Childs GV,MacNicol AM

更新日期：2021-03-01 00:00:00

abstract：INTRODUCTION:Social distancing requirements during COVID-19 pose a challenge to conducting traditional academic detailing, which typically involves in-person peer education visits to improve patient outcomes. The main alternative is to conduct virtual academic detailing delivered through web-based technology, but this ...

authors： Smart MH,Mandava MR,Lee TA,Pickard AS

更新日期：2021-03-01 00:00:00